105 GLUCOCORTICOID SENSITIVITY OF HUMAN NEONATAL LEUKOCYTES

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Glucocorticoid in Neonatal Rat Heart

The ability of cells to directly respond to glucocorticoids and aldosterone is a function of GR and MR expression, and coexpression of 11 -hydroxysteroid dehydrogenases (11 HSDs), which convert glucocorticoids and their 11-ketometabolites into either receptor inactive or active derivatives. The aim of the present study was to determine the cellular expression of GR, MR, 11 HSD1, and 11 HSD2 in ...

متن کامل

Clinical aspects of glucocorticoid sensitivity.

Recent studies demonstrate that primary (hereditary) abnormalities in the glucocorticoid receptor gene make 6.6% of the normal population relatively "hypersensitive" to glucocorticoids, while 2.3% are relatively "resistant." These abnormalities might explain why some individuals develop severe adverse effects during low dose glucocorticoid therapy, while others do not develop side effects even ...

متن کامل

Abnormal Mobility of Neonatal Polymorphonuclear Leukocytes

A portion of this work was presented at the meeting of the Society of Pediatric Research (Immunology Section) in San Francisco, Calif., 29 April 1981. Address reprint requests to Dr. Anderson, Pediatrics Infectious Diseases, Texas Children's Hospital, Houston, Tex. 77030. Receivedfor publication 9 March 1981 and in revisedform 3 June 1981. failed to demonstrate expected decreased adherence valu...

متن کامل

Sensitivity And Specificity Of Procalcitonin In Diagnosis Of Neonatal Sepsis

  Background and Objective: According to the fact that neonatal infection is a challenging diagnosis field, several studies have tried to test sensitivity and specificity of diagnostic tests. This study was conducted to evaluate the sensitivity and specificity of procalcitonin (PCT) as a single early marker of neonatal sepsis. Materials and Methods: In this study, 150 neonates admitted to NIC...

متن کامل

Glucocorticoid effects on the uptake of antibiotics by human polymorphonuclear leukocytes

The effects of glucocorticoids on the uptake of 8 antibiotics by human polymorphonuclear leukocytes (PMNs), and the subsequent bactericidal activity of PMNs with 5 of the antibiotics, were examined. The experiments demonstrated that a synthetic glucocorticoid, methylprednisolone at a concentration of more than 50 mg/I, inhibited the uptake of clindamycin, erythromycin and josamycin, but didn't ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Pediatric Research

سال: 1994

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-199407000-00105